Genetic Engineering was inspired by Andy's interest in the subject. Rather than take a reactionary stance, Andy was more interested in the benefits of genetic engineering, such as the eradication of genetically transmitted diseases.

4-Neu is a tribute to 70's German band Neu! - a band, like Kraftwerk, that were a big influence on Andy McCluskey and Paul Humphreys prior to OMD.

The female vocal on Genetic Engineering is Maureen Humphreys - Paul Humphreys' wife at the time.

The robotic voice is actually a Speak And Spell - a childrens electronic spelling toy.